Anal HR-HPV prevalence assessed with the cobas® HPV Test in an HIV-infected population of men who have sex with men.

The mean age was 37 years. Cytological results: 40% – NILM, 17.9% – ASCUS, 24.2% – LSIL, 4.2% – HSIL and 1.1% – AGC. The overall prevalence of HR-HPV was of 80.8%. In 76.9% of the cases, infection occurred with multiple HR-HPV genotypes. The “other” HR-HPV pattern was the most prevalent HR-HPV genotype.

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Considering age, HPV-16 prevalence was 50.0% and 28.6% in patients under and over 30 years, respectively. A histological specimen was obtained from 17 patients and 82.4% of them had AIN.1 – HIV-infected MSM is a highly HR-HPV genotype infected population; 2 – The multiple infection pattern was the most prevalent; 3 – “Other”, an HPV subtype was the most prevalent pattern; 4 – The prevalence of HPV infection and multiplicity of infection was directly related to the severity of the cytological abnormalities and age; 5 – HPV-16 prevalence was more prevalent in patients under 30 years.